Paradigm4 News & Events

12.19.2022 | Eurolab || Intelligent Design

Dr. Zach Pitluk and Dr. Srikant Sarangi on preparing the way for AI/ML to impact drug discovery and development. » FULL ARTICLE

10.30.2022 | World Pharma Today || Foundational partnership with Paradigm4 enables Alnylam Pharmaceuticals to rapidly accelerate RNAi- based drug target discovery

Paradigm4’s REVEAL Integrative Analytics platform enables Alnylam Pharmaceuticals to discover novel, genetically-validated drug targets from population scale biobank genotype-phenotype datasets and underlies the extraordinary pace ... » FULL ARTICLE

10.28.2022 | European Pharmaceutical manufacturer || Paradigm4 and Alnylam partnership to accelerate RNAi- based drug discovery

Paradigm4’s REVEAL Integrative Analytics platform enables Alnylam Pharmaceuticals to discover novel, genetically-validated drug targets from population scale biobank genotype-phenotype datasets and underlies the pace and ... » FULL ARTICLE

10.26.2022 | LABIOTECH || Partnership between Paradigm4 and Alnylam accelerates drug target discovery

New genetically-validated drug targets are found at accelerated speed using population scale biobank genotype-phenotype datasets after a foundational partnership is formed between Paradigm4 and Alnylam. » FULL ARTICLE

10.25.2022 | Biocompare || Introduction to Spatial Metabolomics

Metabolomics—often referred to as the youngest of the omics—provides key insight into phenotype. However, bulk metabolomics requires the homogenization of the sample and is thus ... » FULL ARTICLE

10.25.2022 | Foundational partnership with Paradigm4 enables Alnylam Pharmaceuticals to rapidly accelerate RNAi- based drug target discovery

25th October 2022: Paradigm4’s REVEAL Integrative Analytics platform enables Alnylam Pharmaceuticals to discover novel, genetically-validated drug targets from population scale biobank genotype-phenotype datasets and underlies ... » FULL ARTICLE

10.10.2022 | IPI || Why the right approach to data management will enable the potential of small-molecule RNA sodifiers as drug targets to be fulfilled

Over the past 5 decades or so, the growing understanding that RNA can influence protein function through routes other than direct translation has opened the ... » FULL ARTICLE

09.29.2022 | Biocompare || Peptidomics: Methods in the search for molecular disease signatures

Peptides play important roles in human physiology. They present as intact peptides or can arise from protein degradation. Regardless of the source, peptidomics—the characterization of ... » FULL ARTICLE

09.23.2022 | Bio-IT World || Lessons From the Recent HCA 2022 General Meeting: Applying Single-Cell Data to Clinical Decision Making

The recent Human Cell Atlas (HCA) 2022 General Meeting, hosted in Vienna, Austria, provided a great opportunity for me to catch up on progress towards ... » FULL ARTICLE

07.12.2022 | Clinical Laboratory || Paradigm4 introduces Precision Cell Atlas for REVEAL: SingleCell app

Paradigm4 has introduced the ‘Precision Cell Atlas’ as an integral component of its REVEAL: SingleCell app. The Precision Cell Atlas enables scientists to create a ... » FULL ARTICLE

06.28.2022 | Paradigm4 Launches Precision Cell Atlas™

Paradigm4 has launched the Precision Cell AtlasTM as an integral component of its REVEALTM: SingleCell app. The Precision Cell Atlas enables scientists to create a ... » FULL ARTICLE

06.24.2022 | Pharma’s Almanac || What do you consider the biggest challenge that the pharma/biopharma industry currently faces?

Marilyn Matz, Chief Executive Officer and Co-Founder, Paradigm4 “Genomics’ role in the life science vision “is only as credible as its implementation,” » FULL ARTICLE

05.13.2022 | Paradigm4 Launches REVEAL: Proteomics to Transform the Search for Protein Isoform Biomarkers

BOSTON — Paradigm4 has today unveiled REVEAL™: Proteomics, the newest use case specific app powered by the Paradigm4 FLASH™ high-performance bioinformatics platform. REVEAL: Proteomics unlocks ... » FULL ARTICLE

02.01.2022 | insideBIGDATA || Big Data in Life Sciences – Why ‘doing things the old way’ is the Biggest Barrier to Progress

Zachary Pitluk, Ph.D., Vice President of Life Sciences and Healthcare at Paradigm4, highlights how real insight comes, not from data collection, but from intelligent data ... » FULL ARTICLE

01.21.2022 | Bio-IT World || The Role Of Bioinformatics In Bringing Biobanks To The Forefront Of Scientific Breakthroughs

Life science researchers and drug discovery scientists today work in what, in my view, will be remembered in the future as the beginning of a ... » FULL ARTICLE

01.18.2022 | Biospace || Paradigm4 Joins the Tetra Partner Network to Leverage Tetra Data into High-performing Analytical Computing Applications for Pharmaceutical Customers

TetraScience, the R&D Data Cloud company, announced today that Paradigm4, an integrated scientific data analytics company, has joined the Tetra Partner Network (TPN) so that ... » FULL ARTICLE

11.11.2021 | International Pharmaceutical Technology | 1 Trillion Cells, 50 Million Individuals

Calculating the true value of scientific data storage platforms is the goal of every developer. With millions of cells to analyze, digital solutions are the ... » FULL ARTICLE

10.07.2021 | Paradigm4 launches flexFS

Paradigm4, an integrated scientific data analytics company, has launched flexFS, its elastic cloud file system for flexible and more resource-efficient data storage and scalable computing. » FULL ARTICLE

10.07.2021 | Pharma’s Almanac | What do you think most differentiates the U.S. pharma/biopharma industry or the market?

Paradigm4’s Marilyn Matz reflects on the understanding complex biological phenomena has required concurrent advances in experimental methods and computing power. » FULL ARTICLE

09.01.2021 | Pharma’s Almanac | Integrating Heterogeneous Data to Enable Precision Medicine

Paradigm4’s Marilyn Matz and Zachary Pitluk discuss the challenges of integrating data from heterogeneous sources and how the company’s plaform and apps combine the cutting ... » FULL ARTICLE

08.06.2021 | Manufacturing Chemist | Multidimensional data analysis platforms: meeting new FDA calls for consistent evidence from CGT developers

Recent news that the US Food and Drug Administration (FDA) will ask cell and gene therapy (CGT) developers to provide more consistent evidence with their ... » FULL ARTICLE

07.26.2021 | Proteomics & Metabolomics | Paradigm4 Launches REVEAL: Multi-Omics App for Advanced Cross-Study Analyses

Paradigm4 has launched its REVEAL™: Multi-Omics app, allowing researchers to undertake advanced, cross-study analyses and enable quick searches for genes and proteins across all integrated ... » FULL ARTICLE

07.09.2021 | Biocompare | Are We Ready to Embrace Precision Medicine?

Precision medicine is one of the most talked about trends in healthcare. The promise is improved health outcomes and patient satisfaction, gained through an understanding ... » FULL ARTICLE

07.01.2021 | Drug Discovery World | Are scalable data science platforms the way forward?

Marilyn Matz, CEO of Paradigm4, and Zachary Pitluk, Vice President of Life Sciences at Paradigm4, explain why scalable data science platforms are key to supporting ... » FULL ARTICLE

06.25.2021 | Clinical Omics | Pushing the Proteomics envelope

More sensitive technology spurs proteomic and metabolomic biomarker identification, clinical use. (Complete article on page 21) » FULL ARTICLE

06.15.2021 | Clinical Laboratory | Paradigm4 unveils analytical development data management tool to unlock Allotrope data format (ADF) ‘treasure trove’

Addressing the vital economic challenge of uncovering new critical quality attributes (CQAs), Paradigm4’s REVEALTM Analytical Development app enables data analysts… » FULL ARTICLE

05.14.2021 | datanami | Key Questions to Ask of Your Scientific Data Platform for Single Cell Analysis

The idea of precision medicine – delivering the right drug treatment to the right patient at the right time and at the right dose – ... » FULL ARTICLE

04.15.2021 | R&D World | The need for next generation analytics to extract valuable insights from genomic biobank data

Precision medicine is poised to transform healthcare, with biobanks being identified as a key enabler to bring it to fruition by 2030 by putting new, ... » FULL ARTICLE

04.13.2021 | GEN: Genetic Engineering and Biotechnology News | The Vast Potential of Single-Cell Analysis

Single-cell analysis has great promise… but how can we get there? by Zachary Pitluk » FULL ARTICLE

04.02.2021 | Genentic Engineering & Biotechnology News | AI in Drug Discovery Starts to Live Up to the Hype

The past few years have seen several flashy demonstrations of how artificial intelligence (AI) algorithms may transform biomedical research, particularly with respect to drug discovery. » FULL ARTICLE

03.30.2021 | The Analytical Scientist | The Vast Potential of Single-Cell Analysis

Single-cell analysis has great promise… but how can we get there? by Zachary Pitluk » FULL ARTICLE

02.15.2021 | 54 Gene enlists Paradigm4 app for African Health Information Ecosystem

Paradigm4 has signed an agreement with 54Gene allowing the latter to use the former’s Reveal Biobank App to explore, characterise and query 54Gene’s African Health ... » FULL ARTICLE

02.03.2021 | BIO-IT World | Is Precision Medicine Ready For Data From Billions Of Cells?

Popular opinion is that two big shifts have changed the game for bioinformatics. The first is a technology development—single cell ‘omics—that began just over 10 ... » FULL ARTICLE

01.20.2021 | Technology Networks | How Can Data Platforms Unlock the Power of Single-Cell Analysis?

Single-cell technologies have positioned themselves at the forefront of biomedical research. These platforms allow researchers to bypass the uncertainties of bulk data and instead interrogate ... » FULL ARTICLE

01.20.2021 | Manufacturing Chemist | The increasing power of single-cell omics: changing the future of medicine

Advances in the single-cell genomic analysis of cells and tissues, including the required computational methods, have now put systematic, high-resolution and comprehensive reference maps of ... » FULL ARTICLE

01.12.2021 | 54gene Enlists Paradigm4’s Science-Ready Data Solution for its African Health Information Ecosystem

12 JANUARY 2021: Paradigm4, specialist in scientific data management and scalable computation, has signed an agreement with 54gene, a health technology company deriving insights from the world’s ... » FULL ARTICLE

12.17.2020 | Technology Networks | How Can Data Platforms Unlock the Power of Single-Cell Analysis?

Single-cell technologies have positioned themselves at the forefront of biomedical research. These platforms allow researchers to bypass the uncertainties of bulk data and instead interrogate ... » FULL ARTICLE

12.11.2020 | Pharma’s Almanac | Enabling Pharma Researchers to Think Differently with Effective Data Manipulation

Pharma researchers are tasked with organizing disparate data, which detracts from time spent understanding disease mechanisms and enabling the development of more effective drugs. Paradigm4 ... » FULL ARTICLE

11.19.2020 | GenomeWeb: Paradigm4 Moves Into Single-Cell Data, Helps Pharma Address COVID-19

Neil Versel » FULL ARTICLE

11.19.2020 | Allotrope Connect Fall 2020 Conference presentation: Leveraging millions of ADF files and enabling Data Science in Pharma with Python and R

Zach Pitluk, Ph.D. » FULL ARTICLE

09.25.2020 | BioPharma Trend: A new way to work with data in life sciences

Interview with Marilyn Matz, CEO and Co-founder at Paradigm4, and 2020 NACD Directorship 100™ honoree, and her colleague Dr. Zachary Pitluk, VP of Life Sciences ... » FULL ARTICLE

06.21.2020 | AWS Healthcare & Life Science (HCLS) Web Day 2020

Oh the Places You’ll Go (with 1 billion regressions an hour) explores the partnership with Alnylam to access and understand the data from the UK ... » FULL ARTICLE