Paradigm4 Publications

06.24.2020 | Rapid Single Cell Evaluation of Human Disease and Disorder Targets Using REVEAL SingleCell™

biorxiv Namit Kumar, Ryan Golhar, Kriti Sen Sharma, James L Holloway, Srikant Sarangi, Isaac Neuhaus, Alice M. Walsh, Zachary W. Pitluk

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05.19.2020 | Genome-wide association study of circulating liver enzymes reveals an expanded role for manganese transporter SLC30A10 in liver health

bioRxiv

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09.21.2019 | Transthyretin-stabilizing mutation T119M is not associated with protection against vascular disease or death in the UK Biobank

BioRXiv Parker MM, Damrauer SM, Rader DJ, Ticau S, Erbe D, Hinkle G, Nioi P.

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08.01.2019 | The V122I Mutation in Hereditary Transthyretin-Mediated Amyloidosis is Significantly Associated with Polyneuropathy

Journal of Cardiac Failure Parker MM, Damrauer SM, Rader DJ, Ticau S, Erbe D, Hinkle G, Nioi P.

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06.09.2019 | Components of genetic associations across 2,138 phenotypes in the UK Biobank highlight adipocyte biology

Nature Communications Yosuke Tanigawa, Jiehan Li, Johanne M. Justesen, Heiko Horn, Matthew Aguirre, Christopher DeBoever, Chris Chang, Balasubramanian Narasimhan, Kasper Lage, Trevor Hastie, Chong Y. Park, Gill Bejerano, Erik Ingelsson & Manuel A. Rivas

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06.01.2018 | Second Largest Eigenvalue of the Transition Probability Matrix for the Markov Chain Constructed from the Arterial Blood Pressure Waveform is Not Correlated to Shock Index in Hemorrhagic Human Subjects

Aisthesis: The Interdisciplinary Honors Journal M. Bikak, P. Brown, Z. Pitluk. M. Adibuzzaman

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04.24.2018 | Medical relevance of protein-truncating variants across 337,205 individuals in the UK Biobank study

Nature Communications Christopher DeBoever, Yosuke Tanigawa, Malene E. Lindholm, Greg McInnes, Adam Lavertu, Erik Ingelsson, Chris Chang, Euan A. Ashley, Carlos D. Bustamante, Mark J. Daly & Manuel A. Rivas

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04.14.2018 | Bayesian model comparison for rare variant association studies of multiple phenotypes

bioRxiv Christopher DeBoever, Matthew Aguirre,Yosuke Tanigawa, Chris C. A. Spencer, Timothy Poterba, Carlos D. Bustamante, Mark J. Daly, Matti Pirinen, Manuel A. Rivas

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07.20.2017 | Deep Learning for Robust Phenotyping of High Content Cellular Images

High Content Analysis; Roohani Y, Hoffman A, Musso R, Richmond N.

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03.02.2017 | Closing the Data Loop: An Integrated Open Access Analysis Platform for the MIMIC Database

Computing in Cardiology Adibuzzaman M, Musselman K, Johnson A, Brown P, Pitluk Z, Grama A.

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09.24.2016 | Benchmarking SciDB data import on HPC systems. IEEE High Performance

Extreme Computing Conference Samsi S, Brattain L, Arcand W, Bestor D, Bergeron B, Byun C, et al.

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01.01.2016 | Predicting Significance of Unknown Variants in Glial Tumors Through Sub-Class Enrichment

Pacific Symposium on Biocomputing. Fichtenholtz AM, Camarda ND, Neumann EK.

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07.20.2015 | Analysis of Metabolomics Datasets with High-Performance Computing and Metabolite Atlases

Metabolites Yao Y, Sun T, Wang T, Ruebel O, Northen T, Bowen BP.

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